Clinically-backed ingredients for healthy aging

Healthy aging is no longer a concern limited to Baby Boomers or Gen X.

Millennials and Gen Z are also adopting a proactive approach by seeking supplements and lifestyle solutions that support mobility, beauty, muscle mass, hormone balance, cognitive function, and overall cellular health.¹

Daily aches and discomfort are no longer accepted as inevitable; instead, consumers actively pursue scientifically backed products that provide meaningful benefits and promote a longer, healthier life.

According to Vitamin Shoppe’s ‘Health and Wellness 2025 Trends Report’, 43% of consumers depend on vitamins and supplements to improve longevity, while the cellular health and healthy aging categories saw a 91% growth in Q1 alone.² These modern consumers are tech-savvy and expect formulations that are clinically validated to guarantee both effectiveness and safety.

Several ingredients attract consumer interest because of their proven health benefits and increasing popularity. Collagen, for example, is essential for maintaining skin elasticity, bone strength, muscle health, and the integrity of connective tissue, but its production naturally declines with age. Its popularity is reflected in social media metrics, with TikTok searches increasing by over 745% year-on-year, according to Spate.³

Turmeric, particularly its active compound curcumin, is recognized for its anti-inflammatory properties and support for overall wellness. However, standard turmeric has low bioavailability, which can limit its effectiveness for consumers. NAD+, or Nicotinamide Adenine Dinucleotide, has also gained attention, with searches increasing by 500%.² This coenzyme is associated with energy production, metabolic health, cognitive support, and overall longevity.

Additional ingredients that support longevity, such as Resveratrol, a powerful antioxidant, are valued for promoting bone and cardiovascular health. Meanwhile, Astaxanthin provides strong antioxidant effects for the skin, eyes, and immune system; however, these are again examples of ingredients that suffer from low bioavailability.

Omega-3 fatty acids remain a staple for supporting cardiovascular, cognitive, and joint health; however, traditional formulations often face absorption issues, which can cause unwanted side effects such as fishy burps.

Enhancing bioavailability of ingredients

Gencor has become a leader in longevity-focused nutraceuticals, emphasizing research and clinically validated ingredients. With over 80 clinical studies completed, Gencor shows a dedication to providing ingredients that offer measurable health benefits. Its partnership with Pharmako Biotechnologies helps enhance the bioavailability of often hard-to-formulate ingredients, thereby increasing efficacy and ensuring consumers receive the full benefits of each supplement.

One of the most innovative ingredients is HydroCurc®, a cold-water dispersible form of curcumin enhanced with Pharmako’s LipiSperse® technology, making it the world’s most bioavailable curcumin in a single dose.⁴ Consumer interest in curcumin has increased by over 1,500% on TikTok, reflecting the rising demand for effective, bioavailable turmeric solutions.²

HydroCurc addresses common bioavailability issues associated with standard curcumin, as shown through validated PK studies, and is clinically proven to support inflammation reduction, joint health, and cognitive function.

PlexoZome® NR is another breakthrough ingredient, providing a true liposomal form of Nicotinamide Riboside to boost absorption and support cellular health, energy production, and metabolic function. PlexoZome is a pioneering technology developed by Pharmako that creates authentic liposomal structures, verified through cryo-TEM imaging and zeta potential measurements, to ensure the quality and integrity of the science behind this advanced delivery method.⁵

Another innovative technology scientifically proven to improve bioavailability in the body is CPO®, a compressible powder oil technology developed by Pharmako. Specifically, CPO Astaxanthin contains AstaReal’s clinically validated Astaxanthin, offering the highest quality, stability, and concentration available on the market.

CPO provides a highly absorbable form of the carotenoid, which is known for supporting skin, eye, and antioxidant health, giving consumers confidence that their supplements are based on solid data.

When we consider healthy aging, we often emphasize our bones and joint health. VeriSperse® is a cold water dispersible (CWD) trans-resveratrol powder. Using award-winning, patented LipiSperse dispersion technology combined with high-quality trans-resveratrol, VeriSperse offers double the bioavailability of standard resveratrol.⁶ It supports bone health and cellular defense against oxidative stress – both essential for healthy living and longevity.

Additionally, AquaCelle® Omega-3 is a highly bioavailable ingredient that uses patented micellar technology to enhance absorption by up to 600%, supporting cardiovascular, cognitive, and joint health. AquaCelle Omega-3 also prevents common side effects of fish oil, like fishy reflux, because its self-emulsifying micellar technology encapsulates lipophilic active compounds for better absorption, leading to higher bioavailability, effectiveness, and stability.

Clinically-backed ingredients for longevity

Gencor’s key ingredient for longevity is the bioavailable form of Palmitoylethanolamide (PEA), Levagen®+. Enhanced with LipiSperse technology, Levagen+ has over 16 clinical studies demonstrating its ability to reduce inflammation and discomfort, support immunity, aid recovery, manage stress, and promote restorative sleep.

Levagen+ also includes recently published research showing its effectiveness in topical formulations for inflammation. With broad versatility and increased bioavailability, Levagen+ offers consumers a science-backed solution and formulators a stable, formulation-friendly ingredient.

Focusing on healthy aging in both male and female populations, Gencor has developed targeted solutions to tackle age-related challenges. For men, Testofen®, a standardized fenugreek extract, has been clinically proven to support testosterone, muscle mass, and strength, helping to alleviate symptoms associated with andropause.

For women, Gencor identified a market gap in women’s health and developed Libifem®, a standardized fenugreek extract specifically designed to support women at all stages of life. Libifem is clinically proven to improve muscle strength, support healthy estradiol levels for increased vitality, and promote better sexual health. It also helps reduce common menopause symptoms, offering a comprehensive approach to female healthy aging.

Consumers are increasingly favoring supplements that are both effective and scientifically proven. As interest in proactive healthy aging, functional nutrition, and wellness grows, the demand for bioavailable, clinically supported ingredients continues to rise.

Gencor’s research-driven formulations, combined with advanced delivery technologies, offer solutions that target key aspects of healthspan, including mobility, cognitive support, cellular health, hormonal balance, and muscle function. These solutions help consumers maintain an active, vibrant lifestyle while proactively addressing the effects of aging.

Author: Krysta O’Connor, Brand Manager at Gencor

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