Skate cartilage extract found to have protective effects against liver damage: South Korean study

By Cheryl Tay contact

- Last updated on GMT

A chondroitin sulfate-rich extract from the skate fish could protect against liver damage. ©iStock
A chondroitin sulfate-rich extract from the skate fish could protect against liver damage. ©iStock

Related tags: Inflammation

Cartilage extracted from the skate fish can protect against liver damage, according to a recent South Korean study.

The study, led by Pusan National University, investigated the protective effects of a chondroitin sulfate-rich extract (CSE) from skate cartilage against liver damage caused by lipopolysaccharide (LPS) in mice.

Researchers compared how the CSE fared compared with chondroitin sulfate (CS) from shark cartilage — which had previously been shown to protect against inflammation of the liver.

Beneficial effects

They found the CSE mice were protected against LPS-induced liver damage due to the CSE reducing oxidative stress. These beneficial effects were noted to be comparable to those of CS.

Harmful enzymes released into the circulatory system in the event of liver structure were noticeably alleviated by the CSE, showing that “skate CSE has a preventative effect against LPS-induced liver damage”​.

Additionally, both the CSE and CS were found to be able to lower LPS-induced liver inflammation in the mice by downregulating the “gene expression of pro-inflammatory cytokines and enzymes”​.

At the same time, the CSE was said to be able to “effectively ameliorate LPS-induced hyperlipidemia”​, which often accompanies infectious and inflammatory diseases; the extract was shown to have significantly lowered serum lipid levels.

 

Source: Marine Drugs

https://doi.org/10.3390/md15060178

“Chondroitin Sulfate-Rich Extract of Skate Cartilage Attenuates Lipopolysaccharide-Induced Liver Damage in Mice”

Authors: Yeong Ok Song, et al.

Related news

Show more

Related products

show more

Lute-gen®: Telomere protection & healthy ageing

Lute-gen®: Telomere protection & healthy ageing

Bio-gen Extracts Pvt. Ltd. | 27-Apr-2020 | Technical / White Paper

Ageing is an inevitable part of every individual's lifetime, but it is up to each individual to make the right choice to enable them to age healthily....

CryoCap: Protecting Vit K2 in Mineral Combinations

CryoCap: Protecting Vit K2 in Mineral Combinations

NattoPharma USA, Inc. | 02-Sep-2019 | Technical / White Paper

Suppliers must deliver proven material they can assure is stable in any formulation. NattoPharma is that supplier.
Many parameters influence formulation...

Related suppliers

Follow us

Featured Events

View more

Products

View more

Webinars

Nutra Champions Podcast

Nutra Champions Podcast